eIF4A3-IN-14 (compound 51) is a Silvestrol (HY-13251) analogue. eIF4A3-IN-14 interferes the assembling of eIF4F translation complex with EC50s of 40 and 50 nM for myc-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-14 can be used for the research of human cancer pathogenesis[1].
Molecular Weight:
477.51
Purity:
99.81
CAS Number:
[1402931-65-0]
Formula:
C27H27NO7
Target:
Eukaryotic Initiation Factor (eIF)
Application Notes:
MCE Product type: Reference compound
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