Tri-GalNAc-DBCO is a synthetic ligand composed of three GalNAc units connected to DBCO. Tri-GalNAc-DBCO can act as a ligand for the sialic acid-degrading protein receptor (ASGPR), and can be coupled with targeting proteins or small molecules to form GalNAc-LYTACs. Tri-GalNAc-DBCO specifically binds to ASGPR and, through receptor-mediated endocytosis, guides the coupled molecules to lysosomes for degradation[1][2][3].
Molecular Weight:
1730.94
Purity:
99.97
CAS Number:
[2999748-27-3]
Formula:
C82H127N11O29
Target:
LYTACs
Application Notes:
MCE Product type: Reference compound
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