HKB99 is an allosteric inhibitor of phosphoglycerate mutase 1 (PGAM1). HKB99 induces apoptosis. HKB99 inhibits the formation of invasive pseudopodia and inhibits migration. HKB99 increases the oxidative stress, activates JNK/c-Jun and suppresses AKT and ERK. HKB99 can be used for the research of non-small-cell lung cancer (NSCLC)[1][2].
Molecular Weight:
450.46
Purity:
98.58
CAS Number:
[2414908-90-8]
Formula:
C23H18N2O6S
Target:
Akt,Apoptosis,ERK,Phosphatase,Reactive Oxygen Species (ROS)
Application Notes:
Reference compound
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