NPD10084 is a pyruvate kinase PKM2 inhibitor that inhibits non-glycolytic signaling in cancer cells. NPD10084 disrupts the interaction between PKM2 and beta-catenin or STAT3 and inhibits downstream signaling. NPD10084 has antiproliferative activity against colorectal cancer cells in vitro and in vivo[1].
Molecular Weight:
345.39
Purity:
99.69
CAS Number:
[1040706-91-9]
Formula:
C21H19N3O2
Target:
Pyruvate Kinase
Application Notes:
MCE Product type: Reference compound
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