GSK137 is an orally active, potent and selective B-cell lymphoma 6 (BCL6) inhibitor. GSK137 blocks the interaction between BCL6 and corepressors (e.g., SMRT), reducing the number of germinal center B cells. GSK137 is promising for research of autoimmune diseases such as systemic lupus erythematosus (SLE) and B-cell-related tumors such as diffuse large B-cell lymphoma[1].
Molecular Weight:
374.41
CAS Number:
[2728727-91-9]
Formula:
C21H19FN6
Target:
BCL6
Application Notes:
MCE Product type: Reference compound
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