ZJH-16 (Compound 11e) is an orally active EED inhibitor (IC50 = 2.72 nM, Kd = 4.4 nM). ZJH-16 inhibits the growth of lymphoma cells and reduces H3K27 trimethylation levels. ZJH-16 inhibits tumor growth in lymphoma animal models. ZJH-16 can be used for research on lymphoma and other cancers[1].
Molecular Weight:
330.34
CAS Number:
[2877017-58-6]
Formula:
C18H14N6O
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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