(S)-Bleximenib (oxalate) is a S-Enantiomer of Bleximenib oxalate (HY-148669A). Bleximenib (JNJ-75276617) oxalate is an orally active and selective menin-KMT2A inhibitor, with IC50 values of 0.1 nM, 0.045 nM, and 0.066 nM for humans, mice, and dogs, respectively. Bleximenib oxalate can inhibit the proliferation and induce apoptosis and differentiation of tumor cells. Bleximenib oxalate can be used in the research of tumors such as leukemia[1].
Molecular Weight:
689.82
Purity:
98.37
Formula:
C34H52FN7O7
Target:
Apoptosis,FLT3,Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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