M47 is a molecular glue that selectively destabilizes Cryptochrome 1 (CRY1) and increases degradation of the CRY1 in the nucleus. M47 enhances apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines and enhances life span in p53 knockout mice. M47 can be used in research of cancer[1].
Molecular Weight:
471.93
Purity:
99.96
CAS Number:
[890808-56-7]
Formula:
C28H22ClNO4
Target:
Apoptosis,Cryptochrome,Molecular Glues
Application Notes:
MCE Product type: Reference compound
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