GCGR antagonist 2, a Furan-2-carbohydrazide, is an orally active glucagon receptor antagonist. GCGR antagonist 2 binds to hGluR with an Kd value of 2.3 nM, and inhibits rat receptor with an IC50 value of 0.43 nM. GCGR antagonist 2 inhibits glucagon-stimulated glycogenolysis[1][2].
Molecular Weight:
450.53
Purity:
99.76
CAS Number:
[280134-25-0]
Formula:
C28H26N4O2
Target:
GCGR
Application Notes:
MCE Product type: Reference compound1
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