E722-2648 TFA is an inhibitor targeting the BCL9 and beta-catenin complex with antitumor activity. E722-2648 TFA blocks complex formation by disrupting the interaction between the two proteins, thereby inhibiting beta-catenin-mediated transcriptional activity and downregulating the expression of WNT target genes. E722-2648 TFA effectively inhibits tumor growth in colon cancer xenograft models and colorectal cancer mouse models. E722-2648 TFA can be used for the research of colon cancer and colorectal cancer[1][2].
Molecular Weight:
504.63
Purity:
96.33
Formula:
C23H31F3N2O3S2
Target:
Bcl-2 Family,Wnt,beta-catenin
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
