NAMPT activator-3, a NAT derivative, is a NAMPT activator with an EC50 of 2.6 µM and a KD of 132 nM. NAMPT activator-3 effectively protects cultured cells from FK866 (HY-50876)-mediated toxicity. NAMPT activator-3 exhibits strong neuroprotective efficacy in a chemotherapy-induced peripheral neuropathy (CIPN) mouse model without any overt toxicity[1].
Molecular Weight:
324.37
Purity:
99.71
CAS Number:
[2790481-63-7]
Formula:
C19H20N2O3
Target:
NAMPT
Application Notes:
MCE Product type: Reference compound
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