PRMT5-IN-19, CAS [[2783961-86-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-149005
Supplier Catalog Number:
HY-149005
Alternative Catalog Number:
MCE-HY-149005-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PRMT5-IN-19 (Compound 41) is an selective orally active non-nucleoside PRMT5 inhibitor with IC50 values of 23.9 nM (radioactive biochemical assay) and 47 nM (AlphaLISA assay). PRMT5-IN-19 can occupy the SAM-binding pocket in PRMT5 and block methyltransferase activity, which displays good selectivity over other PRMTs and PKMTs. PRMT5-IN-19 inhibits cell proliferation by inducing cell apoptosis, and can be used for cancer-related research[1].
Molecular Weight:
396.48
CAS Number:
[2783961-86-2]
Formula:
C25H24N4O
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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