Variegatic acid, CAS [[20988-30-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-149151
Supplier Catalog Number:
HY-149151
Alternative Catalog Number:
MCE-HY-149151-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Variegatic acid is a secondary metabolite derived from basidiomycete fungi. Variegatic acid is a PKCbeta1 inhibitor with an IC50 of 36.2 µM. Variegatic acid inhibits antigen- or calcium ionophore-induced beta-hexosaminidase release (IC50 values of 10.4 µM and 22.2 µM, respectively) and TNF-alpha secretion (IC50 values of 16.8 µM and 20.1 µM, respectively). Variegatic acid suppresses the enzymatic activity of calcium-activated PKCbeta1 and reduces Fe(III) to Fe(II) in a pH-dependent manner, enabling the generation of hydroxyl radicals (OH) through reaction with H2O2, which facilitates the degradation of lignocellulose. Variegatic acid is useful for studying biological degradation and allergic responses.
Molecular Weight:
372.29
CAS Number:
[20988-30-1]
Formula:
C18H12O9
Target:
Endogenous Metabolite,Fungal,Glycosidase,PKC,Reactive Oxygen Species (ROS),TNF Receptor
Application Notes:
MCE Product type: Natural Products
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