MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO-, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO- (lambdaem=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with lambdaem>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N,N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images[1].
Molecular Weight:
687.60
Formula:
C40H36BrN2O2P
Target:
Fluorescent Dye
Application Notes:
MCE Product type: Dye Reagents
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