MKA031 (compound 6y) is a non-competitive MIF inhibitor with an IC50 value of 1.7 µM. MKA031 (compound 6y) interferes with MIF/AIF interaction, MIF nuclear translocation, and N-methyl-N-nitro-N-nitrosoguanidine (MNNG)-induced dependent cell death. MKA031 can be used in the study of chronic hepatitis C virus infection[1].
Molecular Weight:
403.46
Purity:
98.69
CAS Number:
[2951012-00-1]
Formula:
C21H17N5O2S
Target:
Macrophage migration inhibitory factor (MIF)
Application Notes:
MCE Product type: Reference compound
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