Dim16 (hydrochloride), CAS [[2743448-41-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-149310A
Supplier Catalog Number:
HY-149310A
Alternative Catalog Number:
MCE-HY-149310A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Dim16 hydrochloride is a dual PCSK9 inhibitor and HMG-CoAR inhibitor, with an IC50 of 0.8 nM against human PCSK9 and an IC50 of 146.8 µM against HMG-CoAR. Dim16 hydrochloride disrupts the PCSK9-LDLR protein-protein interaction, inhibits the catalytic activity of HMG-CoAR, enhances cellular uptake of extracellular LDL, and suppresses PCSK9-induced platelet aggregation. Dim16 hydrochloride can be used in research related to hypercholesterolemia[1].
Molecular Weight:
620.01
CAS Number:
[2743448-41-9]
Formula:
C29H39ClIN5
Target:
HMG-CoA Reductase (HMGCR),PCSK9
Application Notes:
MCE Product type: Reference compound
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