AD4, CAS [[2918262-09-4]]

Product Overview

• Article Name: AD4, CAS [[2918262-09-4]]
• Biozol Catalog Number: MCE-HY-149428
• Supplier Catalog Number: HY-149428
• Alternative Catalog Number: MCE-HY-149428-1MG,MCE-HY-149428-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AD4 is an artemisinin derivative that is a proteolytic targeting chimera (PROTAC) targeting PCLAF. AD4 can effectively degrade PCLAF in RS4,11 cells (IC50: 0.6 nM), thereby activating the p21/Rb axis and exerting anti-tumor activity. AD4 also prolonged survival of RS4,11-transplanted NOD/SCID mice, with in vivo efficacy[1].

Product Properties

• Molecular Weight: 1035.23
• Purity: 98.01
• CAS Number: [2918262-09-4]
• Formula: C55H78N4O15
• Target: PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound