Berubicin (hydrochloride), CAS [[293736-67-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-14942A
Supplier Catalog Number:
HY-14942A
Alternative Catalog Number:
MCE-HY-14942A-5MG,MCE-HY-14942A-1MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
RTA 744, WP 744, WP 769 (hydrochloride)
Berubicin (RTA 744) hydrochloride is a Doxorubicin (HY-15142A) analog that can cross the blood-brain barrier. Berubicin hydrochloride inhibits P-gp and MRP1-mediated efflux and suppresses glioblastoma multiforme (GBM). Berubicin hydrochloride exerts toxic effects on leukemia cells by activating nuclear factor kappaB (NF-kappaB) and induces apoptosis in neuroblastoma cells. Berubicin hydrochloride can be used in the study of tumors related to the nervous system[1][2][3][4][5].
Molecular Weight:
670.10
Purity:
95.08
CAS Number:
[293736-67-1]
Formula:
C34H36ClNO11
Target:
Apoptosis,Caspase,NF-kappaB
Application Notes:
MCE Product type: Reference compound
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