Berubicin (hydrochloride), CAS [[293736-67-1]]

Product Overview

• Article Name: Berubicin (hydrochloride), CAS [[293736-67-1]]
• Biozol Catalog Number: MCE-HY-14942A
• Supplier Catalog Number: HY-14942A
• Alternative Catalog Number: MCE-HY-14942A-1MG,MCE-HY-14942A-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: RTA 744, WP 744, WP 769 (hydrochloride)

Product Description

Berubicin (RTA 744) hydrochloride is a Doxorubicin (HY-15142A) analog that can cross the blood-brain barrier. Berubicin hydrochloride inhibits P-gp and MRP1-mediated efflux and suppresses glioblastoma multiforme (GBM). Berubicin hydrochloride exerts toxic effects on leukemia cells by activating nuclear factor kappaB (NF-kappaB) and induces apoptosis in neuroblastoma cells. Berubicin hydrochloride can be used in the study of tumors related to the nervous system[1][2][3][4][5].

Product Properties

• Molecular Weight: 670.10
• Purity: 95.08
• CAS Number: [293736-67-1]
• Formula: C34H36ClNO11
• Target: Apoptosis,Caspase,Drug Derivative,NF-kappaB

Application Notes

• Application Notes: MCE Product type: Reference compound