JH-131e-153, CAS [[742104-91-2]] Preis auf Anfrage

Product Overview

• Article Name: JH-131e-153, CAS [[742104-91-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-149489
• Supplier Catalog Number: HY-149489
• Alternative Catalog Number: MCE-HY-149489-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

JH-131e-153, a diacylglycerol (DAG)-lactone, is a small molecule activator of Munc13-1, targeting the C1 domain. The activation sequence of JH-131e-153 on Munc13-1 is WT>I590~R592A~W588A. The C1 domain of Munc13-1 and protein kinase C (PKC) are homologous in sequence and structure. The activation sequence of JH-131e-153 on Munc13-1 and PKC was PKCalpha>Munc13-1>PKCepsilon. JH-131e-153 regulates neuronal processes through Munc13-1 and can be further used in the study of neurodegenerative diseases[1].

Product Properties

• Molecular Weight: 382.53
• CAS Number: [742104-91-2]
• Formula: C22H38O5
• Target: PKC

Application Notes

• Application Notes: Reference compound