UCM-13207 is a selective isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor with a human IC50 of 1.4 µM and human Ka of 7.2 µM. UCM-13207 modulates progerin localization, stability, and levels, reduces DNA damage, increases cellular viability, and decreases tissue senescence. UCM-13207 can be used for the research of Hutchinson-Gilford progeria syndrome[1].
Molecular Weight:
380.52
Purity:
99.61
CAS Number:
[1621536-10-4]
Formula:
C24H32N2O2
Target:
ICMT
Application Notes:
MCE Product type: Reference compound
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