Antitumor agent-123 (Copmound 4d) effectively inhibits multiple kinase targets with anti-cancer effects, including JAK2, JAK3, HDAC1 and HDAC6, with IC50 values of 34.6 and 2.6 µM for JAK2 and JAK3, respectively. Antitumor agent-123 exhibits moderate activity in solid tumor models[1].
Molecular Weight:
412.80
Formula:
C19H14ClFN6O2
Target:
HDAC,JAK
Application Notes:
MCE Product type: Reference compound
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