EZH2-IN-17 (compound 28) is a potent and orally active EZH2 inhibitor with an IC50 value of 0.95 nM. EZH2-IN-17 exhibits high anti-proliferation activity against different lymphoma cell lines including WSU-DLCL2, Pfeiffer and Karpas-422 (IC50 values of 2.36 nM, 1.73 nM, and 1.82 nM, respectively)[1].
Molecular Weight:
598.77
Purity:
98.08
CAS Number:
[2489672-09-3]
Formula:
C36H46N4O4
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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