ICMT-IN-54 (compound 7c) is an adamantyl analogue and an ICMT inhibitor (IC50=12.4 µM), which can inhibit ICMT Methylation. ICMT-in-54 inhibits BFC (N-biotinyl-(6-aminohexanoic)-S-farnesyl-L-cysteine) methylation in saccharomyces cerevisiae expressing ICMT, which is an indirect effect of inhibiting ICMT methylation[1].
Molecular Weight:
487.74
CAS Number:
[908856-14-4]
Formula:
C29H45NO3S
Target:
ICMT
Application Notes:
MCE Product type: Reference compound
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