CDK/HDAC-IN-3 is an orally active HDACs/CDKs dual inhibitor. CDK/HDAC-IN-3 has potent and selective inhibition of CDK9, CDK12, CDK13, HDAC1, HDAC2 and HDAC3 with IC50 values of 98.32 nM, 98.85 nM, 100 nM, 62.12 nM, 93.28nM and 82.87 nM. CDK/HDAC-IN-3 can be used for the acute myeloid leukemia (AML) [1].
Molecular Weight:
509.34
Purity:
99.60
CAS Number:
[2944087-54-9]
Formula:
C24H18Cl2N6O3
Target:
CDK,HDAC
Application Notes:
MCE Product type: Reference compound1
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