PROTAC GSK-3beta Degrader-1 (compound 1) is a degrader targets GSK-3beta degradation with an IC50 value of 833 nM. PROTAC GSK-3beta Degrader-1 contains SB-216763 (a GSK-3beta inhibitor), a PEG linker and a CRBN (E3 ligase liand). PROTAC GSK-3beta Degrader-1 reduces the neurotoxicity induced by Abeta25-35 peptide and CuSO4. PROTAC GSK-3beta Degrader-1 can be used to research in Alzheimers disease[1].
Molecular Weight:
857.73
Purity:
99.05
Formula:
C43H42Cl2N6O9
Target:
GSK-3,PROTACs
Application Notes:
MCE Product type: Reference compound
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