WCA-814 is an androgen receptor (AR) antagonist-Hsp90 inhibitor conjugate. WCA-814 induces the degradation of full-length and AR-V7. WCA-814 has cytotoxic effect in prostatic cancer cells (IC50: 171.2 nM, 26.5 nM for LNCaP, 22Rv1 cell)[1].
Molecular Weight:
861.43
CAS Number:
[2951858-45-8]
Formula:
C46H53ClN10O5
Target:
Androgen Receptor
Application Notes:
MCE Product type: Reference compound
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