Antimalarial agent 23 is an antimalarial benzimidazole with IC50s of 0.08 µM and 0.10 µM for PfNF54 and PfK1, respectively. Antimalarial agent 23 has potent beta-hematin inhibition activity. Antimalarial agent 23 does not directly inhibit the conversion of heme to hemozoin[1].
Molecular Weight:
489.92
Formula:
C24H23ClF3N5O
Target:
Parasite
Application Notes:
MCE Product type: Reference compound
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