SIMR3030 is a potent SARS-CoV-2 PLpro inhibitor with an IC50 value of 0.0399 µg/mL. SIMR3030 shows antiviral activity. SIMR3030 decreases SARS-CoV spike, ORF1b, IFN-alpha, IL-6 mRNA expression. SIMR3030 exhibits a satisfactory safety profile in mice[1].
Molecular Weight:
427.54
CAS Number:
[2708270-99-7]
Formula:
C27H29N3O2
Target:
SARS-CoV
Application Notes:
MCE Product type: Reference compound
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