ATR-IN-23 (Compound 34) is a potent and selective ATR inhibitor with an IC50 of 1.5 nM. ATR-IN-23 has potent antiproliferative effects on LoVo cells and synthetic lethality on HT-29 cells, and can be used in the study of DNA damage response (DDR)-deficient cancers[1].
Molecular Weight:
458.56
CAS Number:
[2923800-62-6]
Formula:
C20H22N6O3S2
Target:
ATM/ATR
Application Notes:
MCE Product type: Reference compound
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