Stemregenin 1 (GMP), CAS [[1227633-49-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-15001G
Supplier Catalog Number:
HY-15001G
Alternative Catalog Number:
MCE-HY-15001G-50MG,MCE-HY-15001G-10MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
SR1 (GMP)
Stemregenin 1 (SR1) (GMP) is a GMP-grade Stemregenin 1 (HY-15001). GMP-grade small molecules can be used as adjuvants in cell therapy. Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with an IC50 of 127 nM. Stemregenin 1 (GMP) can competitively bind to AhR and inhibit its nuclear translocation, inhibiting osteoclastogenesis and promoting hematopoietic progenitor cell expansion by blocking the AhR-c-src-NF-kappaB/p-ERK MAPK-NFATc1 signaling pathway. Stemregenin 1 (GMP) can be used for the study of osteoporosis, in vitro expansion of hematopoietic stem cells, and the study of the mechanism of bone metabolic diseases[1][2][3][4].
Molecular Weight:
429.54
Purity:
99.7
CAS Number:
[1227633-49-9]
Formula:
C24H23N5OS
Target:
Aryl Hydrocarbon Receptor
Application Notes:
MCE Product type: GMP Small Molecules
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