AST 487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM.
Molecular Weight:
529.56
Purity:
98.90
CAS Number:
[630124-46-8]
Formula:
C26H30F3N7O2
Target:
Bcr-Abl,c-Kit,FLT3,RET,VEGFR
Application Notes:
MCE Product type: Reference compound
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