TP0480066 is a selective topoisomerase II inhibitor with IC50s of 1.10 and 62.89 nM for DNA gyrase and topo IV, respectively. TP0480066 shows good activity of againsting various bacterial species including drug-resistant strains. TP0480066 also exhibits potent inhibitory activity to N. gonorrhoeae, can be used in study of gonorrhea[1][2].
Molecular Weight:
371.32
CAS Number:
[2245693-15-4]
Formula:
C18H14FN3O5
Target:
Bacterial,Topoisomerase
Application Notes:
MCE Product type: Reference compound
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