SARS-CoV-2 nsp3-IN-1 (Compound 15c) is a Mac1 (SARS-CoV-2 nsp3 macrodomain) inhibitor with the IC50 value of 6.1 µM. SARS-CoV-2 nsp3-IN-1 can inhibit Mac1 ADP-ribosylhydrolase activity. SARS-CoV-2 nsp3-IN-1 demonstrates notable selectivity for coronavirus macrodomains, especially towards SARS-CoV-2 Mac1[1].
Molecular Weight:
321.33
Purity:
98
CAS Number:
[2892105-43-8]
Formula:
C17H15N5O2
Target:
SARS-CoV
Application Notes:
MCE Product type: Reference compound
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