SRI-37240 is a potent premature termination codons (PTCs) inhibitor. SRI-37240 suppresses CFTR nonsense mutations. SRI-37240 alters cellular translation termination at PTCs in HEK293T cells. SRI-37240 can also restore CFTR function in primary bronchial epithelial cells when combination with G418[1].
Molecular Weight:
385.46
Purity:
98.29
CAS Number:
[883956-47-6]
Formula:
C24H23N3O2
Target:
CFTR
Application Notes:
MCE Product type: Reference compound1
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