Cys-McMMAF is the released payload of AlMcMMAF, an anti-5T4 humanized A1 antibody conjugated to the microtubule disrupting MMAF (HY-15579) via a maleimidocaproyl linker. Cys-McMMAF has antitumor efficacy in two tumor mouse models (H1975 and MDA-MB-361-DYT2 models)[1].
Molecular Weight:
1046.32
Purity:
99.45
CAS Number:
[1160590-05-5]
Formula:
C52H83N7O13S
Target:
Microtubule/Tubulin
Application Notes:
MCE Product type: ADC Related
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