ATIC-IN-1(compound 14) is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 exhibits anti-tumor activity via reduction in cell numbers and cell division rates[1].
Molecular Weight:
463.53
Purity:
99.69
CAS Number:
[1402453-15-9]
Formula:
C21H33N7O5
Target:
Others
Application Notes:
MCE Product type: Reference compound1
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