Farabursen sodium (RGLS8429 sodium, RG1015 sodium) is a miR-17 inhibitor. Farabursen sodium inhibits the function of the miR-17 family, relieves the inhibitory effect on miR-17 target genes including PKD1 and PKD2, and increases the level of PC1/2. Farabursen sodium slows the growth of renal cysts, reduces the ratio of kidney weight to body weight, and decreases the cyst index and proliferation index. Farabursen sodium is applicable to research related to autosomal dominant polycystic kidney disease[1][2].
Molecular Weight:
3066.4 (free acid)
Purity:
93.56
CAS Number:
[2921918-19-4]
Formula:
C95H107F3N32Na8O50P8S8
Target:
MicroRNA
Application Notes:
MCE Product type: Oligonucleotides
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