Diclofenac (Standard) is the analytical standard of Diclofenac. This product is intended for research and analytical applications. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 µM for ovine COX-1 and COX-2, respectively[2]. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].
Molecular Weight:
296.15
Purity:
99.91
CAS Number:
[15307-86-5]
Formula:
C14H11Cl2NO2
Target:
Apoptosis,COX,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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