Diclofenac-d4 (sodium) is the deuterium labeled Diclofenac sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 µM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].
Molecular Weight:
322.16
Purity:
99.49
CAS Number:
[154523-54-3]
Formula:
C14H6D4Cl2NNaO2
Target:
Apoptosis,COX
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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