TSPO ligand-1 is the ligand of AUTAC4 (HY-134640) that can be used in the synthesis of PROTACs. TSPO ligand-1 is a mitochondrial outer membrane transmembrane structural domain protein can bind to AUTAC4 and regulate mitochondrial autophagy to promote targeted mitochondrial renewal. TSPO ligand-1 is also involved in the transport of cholesterol from the outer to inner mitochondrial membrane and serves as a sensitive biomarker of brain injury and neurodegeneration[1][2].
Molecular Weight:
283.71
Purity:
98
CAS Number:
[4560-08-1]
Formula:
C16H10ClNO2
Target:
Autophagy,Ligands for Target Protein for PROTAC
Application Notes:
MCE Product type: Reference compound
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