CHMFL-PI4K-127 (compound 15g) is an orally active, potent and high selective PfPI4K (Plasmodium falciparum PI4K kinase) inhibitor, with an IC50 of 0.9 nM. CHMFL-PI4K-127 exhibits potent activity against 3D7 Plasmodium falciparum, with an EC50 of 25.1 nM. CHMFL-PI4K-127 shows antimalaria efficacy[1].
Molecular Weight:
402.85
Purity:
99.94
CAS Number:
[2377604-81-2]
Formula:
C18H15ClN4O3S
Target:
PI3K,PI4K
Application Notes:
MCE Product type: Reference compound
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