TYK2-IN-12 (compound 30) is an orally active, potent and selective TYK2 (tyrosine kinase 2) inhibitor, with a Ki of 0.51 nM. TYK2-IN-12 inhibits IL-12 induced IFNgamma, with IC50 values of 2.7 and 7.0 µM in human and mouse whole blood, respectively. TYK2-IN-12 can be used for psoriasis research[1].
Molecular Weight:
434.44
Purity:
98.81
CAS Number:
[2244061-66-1]
Formula:
C24H20F2N4O2
Target:
IFNAR,JAK
Application Notes:
MCE Product type: Reference compound1
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