Tubulin/HDAC-IN-1, CAS [[2413587-26-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-150772
Supplier Catalog Number:
HY-150772
Alternative Catalog Number:
MCE-HY-150772-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Tubulin/HDAC-IN-1 is a dual tubulin and HDAC-IN-1 inhibitor through CH/pi interaction with tubulin and hydrogen bond interaction with HDAC8. Tubulin/HDAC-IN-1 inhibits tubulin polymerization and selectively inhibits HDAC8 (IC50: 150 nM). Tubulin/HDAC-IN-1 has cytotoxicity against various human cancer cells, also arrests cell cycle in the G2/M phase and induces cell apoptosis. Tubulin/HDAC-IN-1 can be used in the research of hematologic and solid tumors such as neuroblastoma, leukemia[1].
