JBJ-07-149 is an inhibitor for EGFRL858R/T790M with an IC50 of 1.1 nM. JBJ-07-149 inhibits the proliferation of cell Ba/F3 with IC50 of 4.9 µM and 0.148 µM, without and with presence of Cetuximab (HY-P9905). JBJ-07-149 can be used as ligand for target protein in synthesis of DDC-01-163 (HY-139997)[1].
Molecular Weight:
510.61
Purity:
99.09
CAS Number:
[2140807-58-3]
Formula:
C28H26N6O2S
Target:
EGFR
Application Notes:
MCE Product type: Reference compound
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