SB-423557 is an orally active calcium-sensing receptor (CaR) antagonist (IC50=520 nM), precursor of SB-423562 (IC50=73 nM). SB-423557 is well tolerated in human and increases plasma concentrations of exogenous parathyroid hormone (PTH) and stimulates bone formation[1].
Molecular Weight:
464.60
CAS Number:
[351490-26-1]
Formula:
C28H36N2O4
Target:
CaSR
Application Notes:
MCE Product type: Reference compound
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