S-Methyl-N,N-diethylthiolcarbamate, CAS [[686-07-7]]

Catalog Number: MCE-HY-151229
Article Name: S-Methyl-N,N-diethylthiolcarbamate, CAS [[686-07-7]]
Biozol Catalog Number: MCE-HY-151229
Supplier Catalog Number: HY-151229
Alternative Catalog Number: MCE-HY-151229-50MG,MCE-HY-151229-25MG,MCE-HY-151229-100MG
Manufacturer: MedchemExpress
Category: Biochemikalien
Alternative Names: DETC-Me, DDTC-Me, Diethyldithiocarbamic acid methyl ester
S-Methyl-N,N-diethylthiolcarbamate (DETC-Me, DDTC-Me) is the active metabolite of the aldehyde dehydrogenase inhibitor disulfiram (HY-B0240). It is produced by the methylation of the disulfiram metabolite diethyldithiocarbamate in mouse liver microsomes. S-Methyl-N,N-diethylthiolcarbamate (DETC-Me, DDTC-Me) inhibits rat liver low Km aldehyde dehydrogenase (ALDH) (ID50=15.5 mg/kg). When administered at a dose of 20.6 mg/kg, it decreases mean arterial pressure (MAP) and increases heart rate in rats during ethanol stimulation.
Molecular Weight: 163.30
Purity: 99.77
CAS Number: [686-07-7]
Formula: C6H13NS2
Target: Aldehyde Dehydrogenase (ALDH)
Application Notes: MCE Product type: Reference compound