Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras, K-ras and N-ras with IC50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities.
Molecular Weight:
638.82
Purity:
99.85
CAS Number:
[193275-84-2]
Formula:
C27H31Br2ClN4O2
Target:
Autophagy,Farnesyl Transferase,Ras
Application Notes:
MCE Product type: Reference compound
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