IRAK4-IN-21 (compound 17) is an orally active, potent and selective IRAK4 inhibitor with IC50 values of 5 and 56 nM for IRAK4 and TAK1, respectively. IRAK4-IN-21 effectively inhibits IL-23 production (IC50=0.17 µM) and can be used in studies of autoimmune diseases such as plaque psoriasis and psoriatic arthritis[1].
Molecular Weight:
513.57
Purity:
99.94
CAS Number:
[2170694-04-7]
Formula:
C28H28FN7O2
Target:
IRAK
Application Notes:
MCE Product type: Reference compound
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