VVD-118313 (compound 5a) is a potent, selective JAK1 inhibitor. VVD-118313 targets an isoform-restricted allosteric cysteine to block JAK1-dependent trans-phosphorylation and cytokine signaling. VVD-118313 can be used for research of cancer[1]. VVD-118313 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
429.36
Purity:
99.63
CAS Number:
[2875046-27-6]
Formula:
C19H22Cl2N2O3S
Target:
IFNAR,Interleukin Related,JAK,STAT
Application Notes:
MCE Product type: Reference compound
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