Bemcentinib (Standard) is the analytical standard of Bemcentinib. This product is intended for research and analytical applications. Bemcentinib (R428) is a selective and orally active Axl inhibitor with an IC50 of 14 nM. Bemcentinib retards cancer cell migration and invasion. Bemcentinib exhibits >100-fold selectivity for Axl versus Abl and 50- and >100-fold selectivity over TAM family kinases Mer and Tyro3, respectively, in cells. Bemcentinib blocks tumor spread and prolongs survival in models of metastatic breast cancer[1][2].
Molecular Weight:
506.64
Purity:
97.51
CAS Number:
[1037624-75-1]
Formula:
C30H34N8
Target:
Reference Standards,TAM Receptor
Application Notes:
MCE Product type: Reference Standards
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